Understanding function and specificity of de-ubiquitylating enzymes (DUBs) is a gtech brush bar major goal of current research, since DUBs are key regulators of ubiquitylation events and have been shown to be mutated in human diseases.Most DUBs are cysteine proteases, relying on a catalytic triad of cysteine, histidine and aspartate to cleave the i
Many areas of the cerebral cortex process sensory information or coordinate motor output necessary for control of movement.Disturbances in cortical cholinergic system can affect locomotor coordination.Spinal cord injury causes severe motor impairment and disturbances in cholinergic signalling can aggravate the situation.Considering the impact of co
The aim of this article is to analyse the scientific production on environmental management in companies published in the six main journals on administration in Brazil (RAE, RAEE, RAUSP, RAP, REAd and RAC), during the period between 1996 and 2005.The following aspects were used in order to examine this academic production: quantitative progress of